Photocatalytic Silacyclization of 1,7‐Enynes via Selective Functionalization of Si‐H/Silyl C(sp <sup>3</sup> )‐H Bonds: Access to Densely Functionalized Silacycles
We report a highly efficient protocol for the synthesis of silacycles through oxidative annulation cascade with 1,7‐enynes via selective functionalization of Si‐H/silyl C(sp 3 )‐H bonds of hydrosilanes. Simple N ‐aminopyridinium salt acts as hydrogen atom transfer reagents for the in situ generation of sulfamidyl radical under photoredox catalytic condition. Notably, this protocol demonstrates broad substrate scope with shorter reaction time and viable to the late‐stage functionalization of natural products and pharmaceuticals.
Authors
- Ravikumar Ladumor (ORCID: https://orcid.org/0009-0006-5531-5482)
- Sermadurai Selvakumar
Institutions
- Indian Institute of Technology Indore (IN)
Publication Details
- Journal
- Advanced Synthesis & Catalysis
- Published
- 2026-02-15
- DOI
- https://doi.org/10.1002/adsc.70285
- Primary Topic
- Organoboron and organosilicon chemistry
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Arthritis National Research Foundation
- National Research Foundation
- Department of Science and Technology, Ministry of Science and Technology, India
- Indian Institute of Technology Indore
- Science and Engineering Research Board