Exercise Training Modulates TLR4/NF-κB-Mediated Inflammatory Signaling in Rat Testes after Tramadol Withdrawal.

Exercise training following TRA withdrawal could restore inflammatory balance by suppressing TLR4 and NF-ΚB signaling, normalizing pro- and anti-inflammatory cytokine profiles, and possibly attenuating the iNOS/NO/COXII pathway in Wistar rats.

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Journal
PubMed
Published
2026-02-15
DOI
https://doi.org/10.22074/cellj.2025.2046681.1734
Primary Topic
Veterinary Pharmacology and Anesthesia
Type
article
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0.00
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article

Exercise Training Modulates TLR4/NF-κB-Mediated Inflammatory Signaling in Rat Testes after Tramadol Withdrawal.

J. Azar, Mazdak Razi, Asghar Tofighi, Adel Ahmadyzad
PubMed
Veterinary Pharmacology and Anesthesia
article

Exercise Training Modulates TLR4/NF-κB-Mediated Inflammatory Signaling in Rat Testes after Tramadol Withdrawal.

J. Azar, Mazdak Razi, Asghar Tofighi, Adel Ahmadyzad
article en

Abstract

Exercise training following TRA withdrawal could restore inflammatory balance by suppressing TLR4 and NF-ΚB signaling, normalizing pro- and anti-inflammatory cytokine profiles, and possibly attenuating the iNOS/NO/COXII pathway in Wistar rats.

PubMedVol. 27(1)
Urmia University (IR)
Good health and well-being
Openalex Percentile: Top 52%
Veterinary Pharmacology and Anesthesia
DOISourceOpenAlex
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Exercise Training Modulates TLR4/NF-κB-Mediated Inflammatory Signaling in Rat Testes after Tramadol Withdrawal. — J. Azar, Mazdak Razi, et al. · PubMed (2026) | TGRS Research Map | TGRS