Impact of antiseizure medication taper on electroencephalographic dynamics in focal epilepsy: A stereoelectroencephalographic study
Despite seizure exacerbation during antiseizure medication tapering, seizure-onset location remained stable. This supports the robustness of seizure-based localization even under reduced medication levels and rapid tapering regimens.
Authors
- Alyssa Ho
- Jeffery A. Hall (ORCID: https://orcid.org/0000-0001-8403-8986)
- Radtke Ra
- Kassem Jaber
- Katharina Schiller (ORCID: https://orcid.org/0000-0002-2163-3857)
- Sana Hannan
- Nina J Ghosn (ORCID: https://orcid.org/0000-0003-3471-803X)
- Xiaoyan Wei (ORCID: https://orcid.org/0000-0001-7370-0735)
- John V. Thomas (ORCID: https://orcid.org/0000-0001-9551-9507)
- B. Frauscher
- Hongyi Ye
- D. Southwell
- Tamir Avigdor
- Erin C. Conrad
- Matthew Moye
- Xiaoqiu Shao
- Jean Gotman
- Qun Wang
- Guoping Ren
Institutions
- Montreal Neurological Institute and Hospital (CA)
- Rochester Institute of Technology (US)
- Duke University (US)
- Capital Medical University (CN)
- University Hospital Augsburg (DE)
- Beijing Tian Tan Hospital (CN)
- National Clinical Research Center for Digestive Diseases (CN)
- Sensor-Technik Wiedemann (Germany) (DE)
- Duke Medical Center (US)
- Second Affiliated Hospital of Zhejiang University (CN)
- McGill University (CA)
- Lancaster University (GB)
- University of Pennsylvania (US)
Publication Details
- Journal
- Epilepsia
- Published
- 2026-02-16
- DOI
- https://doi.org/10.1002/epi.70149
- Primary Topic
- Epilepsy research and treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Montreal Neurological Institute and Hospital
- Canadian Institutes of Health Research