CREG1 Attenuates Osteoarthritis Progression by Suppressing Chondrocyte Pyroptosis Through the PINK1/Parkin‐Mediated Mitophagy Pathway
CREG1 protects against OA progression by suppressing NLRP3 inflammasome-driven chondrocyte pyroptosis through activation of PINK1/Parkin-dependent mitophagy, highlighting CREG1 as a potential therapeutic target.
Authors
- Shuzhou Liu (ORCID: https://orcid.org/0000-0003-4874-8571)
- Guangxu Song
- Wei Xu
- Xianming Fei
- Shuhang Dong
Institutions
- Qingdao University (CN)
- University of Science and Technology of China (CN)
- Second Hospital of Shandong University (CN)
- Zhongda Hospital Southeast University (CN)
- Affiliated Hospital of Qingdao University (CN)
- Qilu Hospital of Shandong University (CN)
Publication Details
- Journal
- Biotechnology Journal
- Published
- 2026-02-01
- DOI
- https://doi.org/10.1002/biot.70196
- Primary Topic
- Inflammasome and immune disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00