Does Long‐Term Lower Extremity Strength Training in Adults With Knee Osteoarthritis and Varus Alignment Reduce Knee Joint Loading During Gait?

Among older adults with knee OA and varus alignment, long-term lower extremity strength training results in significant increases in strength but does not significantly alter most measures of knee joint loading during walking relative to an attention control group. The results cast doubt on whether clinically meaningful improvement in lower extremity muscle strength translates to clinically important attenuation in knee joint loading.

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Publication Details

Journal
Arthritis Care & Research
Published
2026-02-16
DOI
https://doi.org/10.1002/acr.80017
Primary Topic
Osteoarthritis Treatment and Mechanisms
Type
article
Field-Weighted Citation Impact
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article

Does Long‐Term Lower Extremity Strength Training in Adults With Knee Osteoarthritis and Varus Alignment Reduce Knee Joint Loading During Gait?

J. S. Marron, Santiago Saldana, Shannon L. Mihalko, Ryan C. Hill et al.
Arthritis Care & Research
Osteoarthritis Treatment and Mechanisms
article

Does Long‐Term Lower Extremity Strength Training in Adults With Knee Osteoarthritis and Varus Alignment Reduce Knee Joint Loading During Gait?

J. S. Marron, Santiago Saldana, Shannon L. Mihalko, Ryan C. Hill, D. Hunter, Paige E. Rice, Paul DeVita, S. P. Messier, Matthew Vigliotti, Kim L Bennell, Brian Pietrosimone, Ali Guermazi, Edward H. Ip
article en

Abstract

Among older adults with knee OA and varus alignment, long-term lower extremity strength training results in significant increases in strength but does not significantly alter most measures of knee joint loading during walking relative to an attention control group. The results cast doubt on whether clinically meaningful improvement in lower extremity muscle strength translates to clinically important attenuation in knee joint loading.

Arthritis Care & Research
Boston University (US), University of North Carolina at Chapel Hill (US), The University of Sydney (AU), The University of Melbourne (AU), East Carolina University (US), Wake Forest University (US)
Good health and well-being
Openalex Percentile: Top 55%
Osteoarthritis Treatment and Mechanisms
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