Is Extended Lymphadenectomy in Biliary Tract Cancers Justified? A Retrospective Comparative Study of Gallbladder Cancer, Perihilar and Intrahepatic Cholangiocarcinoma
Extended LND was associated with a higher rate of postoperative complications and was an independent risk factor in patients undergoing major hepatectomy. However, no clear survival benefit was observed. These findings may suggest that the role of LND in BTC may be primarily diagnostic and that more selective, biology-driven approaches should be considered. Prospective studies are needed for validation.
Authors
- Carina Riediger (ORCID: https://orcid.org/0000-0002-1759-4891)
- Esther Giehl-Brown (ORCID: https://orcid.org/0000-0003-2216-0358)
- Rajan Nikbakhsh (ORCID: https://orcid.org/0000-0002-3185-0871)
- Johannes Schweipert
- Olga Radulova-Mauersberger
- Sarah Bendig
- Jürgen Weitz
Institutions
- Heidelberg University (DE)
- Marienhospital Stuttgart (DE)
- National Center for Tumor Diseases (DE)
- University Hospital Carl Gustav Carus (DE)
- Technische Universität Dresden (DE)
Publication Details
- Journal
- Annals of Surgical Oncology
- Published
- 2026-02-16
- DOI
- https://doi.org/10.1245/s10434-026-19192-1
- Primary Topic
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00