Assessment of geometric distortions and dosimetric impact from implementing 2D-T2-PROPELLER and 3D-T1-LAVA-FLEX in an MRI-only gynecological brachytherapy workflow

An average geometric distortion of 2.4mm was measured for both the 2D-T2-PROPELLER and T1-3D-LAVA-Flex sequence reconstructions; maximum distortions were 7.5 and 6.4mm respectively. Larger geometric distortions are attributed to obtaining measurements on the periphery of the field-of-view and not in the region of applicator and catheter reconstruction. Gamma pass rates of 96.1±2.8% and 96.6±3.1% were found for the 2D-T2-PROPELLER and 3D-T1- LAVA-Flex MRI reconstructions when compared to CT reconstructions. Minimum gamma pass rates were 90.2% and 90.5% respectively. Significant differences in gamma pass rates were not found between T2-2D-PROPELLER and T1-3D-LAVA-FLEX; however, T1-3D-LAVA-FLEX results were skewed towards higher pass rates. T1-3D-LAVA-FLEX also performed significantly better than T2-2D-PROPELLER for a larger number of catheters.

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Publication Details

Journal
Brachytherapy
Published
2026-02-01
DOI
https://doi.org/10.1016/j.brachy.2025.12.012
Primary Topic
Advanced Radiotherapy Techniques
Type
article
Field-Weighted Citation Impact
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article

Assessment of geometric distortions and dosimetric impact from implementing 2D-T2-PROPELLER and 3D-T1-LAVA-FLEX in an MRI-only gynecological brachytherapy workflow

Clara Fallone, Matthew J. Frick, Cassandra Belanger, Daniel Burckhardt Liliya Š. Serbina Igor Malenovský Dalva L. Queiroz Désirée C. Aléné Geonho Cho et al.
Brachytherapy
Advanced Radiotherapy Techniques
article

Assessment of geometric distortions and dosimetric impact from implementing 2D-T2-PROPELLER and 3D-T1-LAVA-FLEX in an MRI-only gynecological brachytherapy workflow

Clara Fallone, Matthew J. Frick, Cassandra Belanger, Daniel Burckhardt Liliya Š. Serbina Igor Malenovský Dalva L. Queiroz Désirée C. Aléné Geonho Cho, Deepak Bhayana, Ali Golestani, Andres Navas-Salazar
article en

Abstract

An average geometric distortion of 2.4mm was measured for both the 2D-T2-PROPELLER and T1-3D-LAVA-Flex sequence reconstructions; maximum distortions were 7.5 and 6.4mm respectively. Larger geometric distortions are attributed to obtaining measurements on the periphery of the field-of-view and not in the region of applicator and catheter reconstruction. Gamma pass rates of 96.1±2.8% and 96.6±3.1% were found for the 2D-T2-PROPELLER and 3D-T1- LAVA-Flex MRI reconstructions when compared to CT reconstructions. Minimum gamma pass rates were 90.2% and 90.5% respectively. Significant differences in gamma pass rates were not found between T2-2D-PROPELLER and T1-3D-LAVA-FLEX; however, T1-3D-LAVA-FLEX results were skewed towards higher pass rates. T1-3D-LAVA-FLEX also performed significantly better than T2-2D-PROPELLER for a larger number of catheters.

Brachytherapy
University of Calgary (CA), Comprehensive Cancer Center Vienna (AT), Alberta Cancer Foundation (CA)
Openalex Percentile: Top 48%
Advanced Radiotherapy Techniques
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