Preliminary Exploration of Fluvastatin Inhibiting Proliferation, Migration and Invasion of Lung Cancer Cells and Reversing Paclitaxel Resistance: Mechanism Exploration Based on Multi-Omics Analysis

This study indicates that fluvastatin has the potential to reverse TAX resistance in lung cancer, and the results of multi-omics analysis provide a theoretical basis for the exploration of potential therapeutic targets in the future.

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Publication Details

Journal
Drug Design Development and Therapy
Published
2026-02-01
DOI
https://doi.org/10.2147/dddt.s579427
Primary Topic
Cancer, Lipids, and Metabolism
Type
article
Field-Weighted Citation Impact
0.00
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article

Preliminary Exploration of Fluvastatin Inhibiting Proliferation, Migration and Invasion of Lung Cancer Cells and Reversing Paclitaxel Resistance: Mechanism Exploration Based on Multi-Omics Analysis

佳苗 清水, Xueting Li, Juan Tang, Hongyu Xu et al.
Drug Design Development and Therapy
Cancer, Lipids, and Metabolism
article

Preliminary Exploration of Fluvastatin Inhibiting Proliferation, Migration and Invasion of Lung Cancer Cells and Reversing Paclitaxel Resistance: Mechanism Exploration Based on Multi-Omics Analysis

佳苗 清水, Xueting Li, Juan Tang, Hongyu Xu, Zedong Du
article en

Abstract

This study indicates that fluvastatin has the potential to reverse TAX resistance in lung cancer, and the results of multi-omics analysis provide a theoretical basis for the exploration of potential therapeutic targets in the future.

Drug Design Development and TherapyVol. Volume 20
Fourth People's Hospital of Sichuan Province (CN), Sichuan Cancer Hospital (CN), Chengdu Second People's Hospital (CN)
Good health and well-being
Openalex Percentile: Top 56%
Cancer, Lipids, and Metabolism
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