Hydrogen sulfide protects dopaminergic neurons via NLRP3 inflammasome inhibition in an MPTP mouse model of Parkinson’s disease

Exogenous H<sub>2</sub>S protects dopaminergic neurons in MPTP-induced PD mice, likely by suppressing NLRP3 inflammasome activation, suggesting its therapeutic potential for PD.

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Publication Details

Journal
Neuroscience Letters
Published
2026-02-17
DOI
https://doi.org/10.1016/j.neulet.2026.138547
Primary Topic
Sulfur Compounds in Biology
Type
article
Field-Weighted Citation Impact
0.00
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article

Hydrogen sulfide protects dopaminergic neurons via NLRP3 inflammasome inhibition in an MPTP mouse model of Parkinson’s disease

Jia Hong, Ke-Ting Liu, Lincen Xiao, Yulian Shui et al.
Neuroscience Letters
Sulfur Compounds in Biology
article

Hydrogen sulfide protects dopaminergic neurons via NLRP3 inflammasome inhibition in an MPTP mouse model of Parkinson’s disease

Jia Hong, Ke-Ting Liu, Lincen Xiao, Yulian Shui, Li Xiao
article en

Abstract

Exogenous H<sub>2</sub>S protects dopaminergic neurons in MPTP-induced PD mice, likely by suppressing NLRP3 inflammasome activation, suggesting its therapeutic potential for PD.

Neuroscience LettersVol. 876
Chengdu Medical College (CN), Sichuan University (CN), West China Hospital of Sichuan University (CN), Southern Medical University (CN)
Good health and well-being
Openalex Percentile: Top 54%
Sulfur Compounds in Biology
DOIOpen Access PDFOpenAlex
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