STUDY OF THE BENZYLATION REACTIONS OF 6-AMINOPURINE AND ITS IMMOBILIZATION PROPERTIES IN HYDROGEL CAPSULES
6-Aminopurine is an important heterocyclic compound exhibiting pronounced biological activity and serving as a precursor of plant growth regulators and coordination ligands. In this study, the benzylation reactions of 6-aminopurine were investigated under various reaction conditions in order to obtain selectively substituted derivatives. The influence of solvent polarity, base strength, temperature, and reagent ratio on the direction of N-alkylation was analyzed, with particular attention to substitution at the N7 and N9 positions of the purine ring. The synthesized benzylated products were isolated and structurally characterized using FT-IR, UV–Vis and NMR spectroscopy, confirming successful modification of the heterocyclic system.
Authors
- Foziljon Saitkulov (ORCID: https://orcid.org/0009-0002-3806-3931)
- Gayrat Haydarov
- Ozoda Kamolova
- 3Qosim Zakhidov
Institutions
- Samarkand State University named after Sharof Rashidov (UZ)
- Tashkent State Agrarian University (UZ)
- Khujand State University (TJ)
- Samarkand State Institute of Foreign Languages (UZ)
Publication Details
- Journal
- Zenodo (CERN European Organization for Nuclear Research)
- Published
- 2026-02-16
- DOI
- https://doi.org/10.5281/zenodo.18657379
- Primary Topic
- Biochemical and Molecular Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00