Clinical characteristics and antimicrobial management of invasive Mycoplasma hominis infection: a case report and literature review
Invasive <i>M. hominis</i> infections, though likely underdiagnosed and underreported, can lead to severe outcomes, particularly in patients with a history of surgery, urinary catheterization, or immunosuppression. Prolonged antimicrobial therapy is associated with improved outcomes, whereas post-transplantation status increases the risk of failure. Doxycycline-containing regimens, especially combined with fluoroquinolones, are a preferred therapeutic strategy. Heightened clinical vigilance and optimized diagnostic and therapeutic approaches are critical to reduce treatment failure.
Authors
- Yunwei Zheng (ORCID: https://orcid.org/0009-0008-8066-0573)
- Shumin Gu (ORCID: https://orcid.org/0000-0001-5442-2274)
- Li Gu (ORCID: https://orcid.org/0000-0002-3318-3902)
- Yi Liu (ORCID: https://orcid.org/0000-0002-1058-0382)
- Shan Zou
- Yanping Xiao
- Yaping Hang
- Qiaoshi Zhong
- Jinyan Xie
- Yanhui Chen
- Fuxing Li
- Xingwei Cao
Institutions
- Nanchang University (CN)
- First Affiliated Hospital of Jiangxi Medical College (CN)
- Hunan Mawangdui Hospital (CN)
Publication Details
- Journal
- Frontiers in Medicine
- Published
- 2026-02-16
- DOI
- https://doi.org/10.3389/fmed.2026.1728188
- Primary Topic
- Orthopedic Infections and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China