Clinical characteristics and antimicrobial management of invasive Mycoplasma hominis infection: a case report and literature review

Invasive <i>M. hominis</i> infections, though likely underdiagnosed and underreported, can lead to severe outcomes, particularly in patients with a history of surgery, urinary catheterization, or immunosuppression. Prolonged antimicrobial therapy is associated with improved outcomes, whereas post-transplantation status increases the risk of failure. Doxycycline-containing regimens, especially combined with fluoroquinolones, are a preferred therapeutic strategy. Heightened clinical vigilance and optimized diagnostic and therapeutic approaches are critical to reduce treatment failure.

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Publication Details

Journal
Frontiers in Medicine
Published
2026-02-16
DOI
https://doi.org/10.3389/fmed.2026.1728188
Primary Topic
Orthopedic Infections and Treatments
Type
article
Field-Weighted Citation Impact
0.00

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article

Clinical characteristics and antimicrobial management of invasive Mycoplasma hominis infection: a case report and literature review

Yunwei Zheng, Shumin Gu, Li Gu, Yi Liu et al.
Frontiers in Medicine
Orthopedic Infections and Treatments
article

Clinical characteristics and antimicrobial management of invasive Mycoplasma hominis infection: a case report and literature review

Yunwei Zheng, Shumin Gu, Li Gu, Yi Liu, Shan Zou, Yanping Xiao, Yaping Hang, Qiaoshi Zhong, Jinyan Xie, Yanhui Chen, Fuxing Li, Xingwei Cao
article en

Abstract

Invasive <i>M. hominis</i> infections, though likely underdiagnosed and underreported, can lead to severe outcomes, particularly in patients with a history of surgery, urinary catheterization, or immunosuppression. Prolonged antimicrobial therapy is associated with improved outcomes, whereas post-transplantation status increases the risk of failure. Doxycycline-containing regimens, especially combined with fluoroquinolones, are a preferred therapeutic strategy. Heightened clinical vigilance and optimized diagnostic and therapeutic approaches are critical to reduce treatment failure.

Frontiers in MedicineVol. 13
Nanchang University (CN), First Affiliated Hospital of Jiangxi Medical College (CN), Hunan Mawangdui Hospital (CN)
National Natural Science Foundation of China
Good health and well-being
Openalex Percentile: Top 54%
Orthopedic Infections and Treatments
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Clinical characteristics and antimicrobial management of invasive Mycoplasma hominis infection: a case report and literature review — Yunwei Zheng, Shumin Gu, et al. · Frontiers in Medicine (2026) | TGRS Research Map | TGRS