Substance Use Disorders and the Psychosis Spectrum: Assessment, Clinical Challenges and Management

The intricate relationship between substance-induced psychotic disorders and primary disorders of the psychosis spectrum requires practitioners to meticulously evaluate patient history, substance use patterns, and clinical symptomatology. Also, the dual diagnosis of SUDs and psychotic disorders exacerbates treatment challenges, often leading to the need to coordinate differing treatment modalities and fragmented care. A nuanced understanding of the interplay between SUDs and the psychosis spectrum is crucial for effective assessment and comprehensive management strategies. In this review, the unique challenges presented by this complex clinical population are examined, and management strategies are explored.

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Publication Details

Journal
Journal of Clinical Medicine
Published
2026-02-16
DOI
https://doi.org/10.3390/jcm15041562
Primary Topic
Schizophrenia research and treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Substance Use Disorders and the Psychosis Spectrum: Assessment, Clinical Challenges and Management

Charidimos Tzagarakis, Thomas Paparrigopoulos, E. Mellos
Journal of Clinical Medicine
Schizophrenia research and treatment
article

Substance Use Disorders and the Psychosis Spectrum: Assessment, Clinical Challenges and Management

Charidimos Tzagarakis, Thomas Paparrigopoulos, E. Mellos
article en

Abstract

The intricate relationship between substance-induced psychotic disorders and primary disorders of the psychosis spectrum requires practitioners to meticulously evaluate patient history, substance use patterns, and clinical symptomatology. Also, the dual diagnosis of SUDs and psychotic disorders exacerbates treatment challenges, often leading to the need to coordinate differing treatment modalities and fragmented care. A nuanced understanding of the interplay between SUDs and the psychosis spectrum is crucial for effective assessment and comprehensive management strategies. In this review, the unique challenges presented by this complex clinical population are examined, and management strategies are explored.

Journal of Clinical MedicineVol. 15(4)
University of Crete (GR), National and Kapodistrian University of Athens (GR), National Public Health Organization (GR)
Good health and well-being
Openalex Percentile: Top 57%
Schizophrenia research and treatment
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