Evaluation of probiotic properties and genome analysis of the new Pediococcus acidilactici strain 46A isolated from Chinese young adults: in vitro and in vivo studies
<i>Pediococcus acidilactici</i> 46A is a safe and functionally active probiotic candidate that attenuates intestinal inflammation and preserves mucosal integrity in a murine model of colitis, supporting its potential application in the prevention or adjunctive treatment of inflammatory gut disorders.
Authors
- Cristina Miceli (ORCID: https://orcid.org/0000-0002-7829-8471)
- Chiara Salvesi
- Matteo Mozzicafreddo (ORCID: https://orcid.org/0000-0001-9835-8446)
- Dennis Fiorini (ORCID: https://orcid.org/0000-0001-5055-6099)
- Vincenzo Bellitto (ORCID: https://orcid.org/0000-0003-4684-8165)
- Daniele Tomassoni (ORCID: https://orcid.org/0000-0001-9062-3305)
- Aristide Toussaint Nguélé (ORCID: https://orcid.org/0009-0007-5056-5981)
- Stefania Silvi
- Anna-Rita Attili
- Polina Makarycheva (ORCID: https://orcid.org/0009-0008-8185-111X)
Institutions
- Università di Camerino (IT)
- Marche Polytechnic University (IT)
- Adventist University Cosendai (CM)
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2026-02-16
- DOI
- https://doi.org/10.3389/fmicb.2026.1725578
- Primary Topic
- Probiotics and Fermented Foods
- Type
- article
- Field-Weighted Citation Impact
- 0.00