Integrated multi-omics analysis reveals epithelial-derived metabolic and adhesive dysregulation in the endometrium of patients with recurrent implantation failure

This integrated multi-omics approach elucidates the complex molecular crosstalk in the non-receptive endometrium. The findings suggest that epithelial metabolic insufficiency and adhesive defects contribute to RIF, offering potential biomarkers and therapeutic targets to improve implantation success.