Enhanced pathogen detection and gut microbiome alterations in pyogenic liver abscess: insights from next-generation sequencing

NGS improves the detection of anaerobes and mixed infections in PLA. The gut microbiota of PLA patients shows marked dysbiosis, suggesting a potential role in disease pathogenesis and future therapeutic targets.

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Publication Details

Journal
Gut Pathogens
Published
2026-02-16
DOI
https://doi.org/10.1186/s13099-026-00799-4
Primary Topic
Amoebic Infections and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Enhanced pathogen detection and gut microbiome alterations in pyogenic liver abscess: insights from next-generation sequencing

Eun Sun Jang, Jeong‐Ju Yoo, Seung Kak Shin, Young Don Kim et al.
Gut Pathogens
Amoebic Infections and Treatments
article

Enhanced pathogen detection and gut microbiome alterations in pyogenic liver abscess: insights from next-generation sequencing

Eun Sun Jang, Jeong‐Ju Yoo, Seung Kak Shin, Young Don Kim, Solbi Kweon, Seong-Hee Kang, Young Kul Jung, Ju Sun Song, Hae Lim Lee, Sung Won Lee, Gwang Hyeon Choi, Hyung Joon Yim, Ji Eun Han, Jung Hwan Yu, Min Jae Kim, Soon Sun Kim, Sang Gyune Kim
article en

Abstract

NGS improves the detection of anaerobes and mixed infections in PLA. The gut microbiota of PLA patients shows marked dysbiosis, suggesting a potential role in disease pathogenesis and future therapeutic targets.

Gut PathogensVol. 18(1)
Gachon University (KR), Green Cross (South Korea) (KR), Asan Medical Center (KR), Seoul National University Bundang Hospital (KR), Ansan University (KR), University of Ulsan (KR), The Catholic University of Korea Bucheon St. Mary's Hospital (KR), Inha University Hospital (KR), Ajou University (KR), Bucheon University (KR)
Good health and well-being
Openalex Percentile: Top 53%
Amoebic Infections and Treatments
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