Genomic landscape of pediatric germ cell tumors reveals oncogenic mutations and copy number alterations

These findings provide insights into the genomic alterations of pediatric GCTs and emphasize the potential for targeted therapies.

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Publication Details

Journal
Frontiers in Oncology
Published
2026-02-16
DOI
https://doi.org/10.3389/fonc.2026.1689022
Primary Topic
Testicular diseases and treatments
Type
article
Field-Weighted Citation Impact
0.00

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article

Genomic landscape of pediatric germ cell tumors reveals oncogenic mutations and copy number alterations

Ana Glenda Santarosa Vieira, Felipe Antônio de Oliveira Garcia, Eduardo Caetano Albino da Silva, LF Lopes et al.
Frontiers in Oncology
Testicular diseases and treatments
article

Genomic landscape of pediatric germ cell tumors reveals oncogenic mutations and copy number alterations

Ana Glenda Santarosa Vieira, Felipe Antônio de Oliveira Garcia, Eduardo Caetano Albino da Silva, LF Lopes, Janaina Mello Soares Galvão, André van Helvoort Lengert, Rui Manuel Reis, Adriane Feijó Evangelista, Ana Flavia Souza Peres Bezerra, Mariana Tomazini Pinto
article en

Abstract

These findings provide insights into the genomic alterations of pediatric GCTs and emphasize the potential for targeted therapies.

Frontiers in OncologyVol. 16
Abbott (Sweden) (SE), Hospital de Câncer de Barretos (BR), Molecular Oncology (United States) (US), University of Minho (PT)
Hospital de Câncer de Barretos, Fundação de Amparo à Pesquisa do Estado de São Paulo, Conselho Nacional de Desenvolvimento Científico e Tecnológico
Openalex Percentile: Top 54%
Testicular diseases and treatments
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