Exploring Transition‐Metal‐Catalyzed Pathways to Indoles From Alkynes and Nitrogen Compounds

Indoles represent a privileged scaffold in organic and medicinal chemistry, prompting continuous efforts toward efficient and versatile synthetic methodologies. In this review, we present a focused survey of recent advances (2020–2025) in the transition‐metal‐catalyzed synthesis of indoles from alkynes and nitrogen sources. Both intra‐ and intermolecular strategies are discussed, highlighting key developments involving cobalt, copper, gold, nickel, palladium, platinum, silver, rhodium, and ruthenium catalysts. Attention is given to mechanistic insights, with detailed discussions provided where necessary to enhance the reader's understanding of the underlying transformations. While this is not an exhaustive compilation of all literature available in the period, we emphasize the most representative and innovative contributions, acknowledging that space limitations may have excluded some high‐quality studies. This review aims to offer a clear and accessible overview of state‐of‐the‐art methodologies, serving as a valuable resource for researchers interested in the design and application of indole‐forming processes from readily available alkynes and nitrogen‐containing precursors.