Enantioselective Access to Cyclopentanone-Fused Dihydrothiophenes

We achieve the Rh/(<i>R</i>,<i>R</i>)-Me-ferrocelane-catalyzed skeletal transformation of 1,2,3-thiadiazoles with cyclopent-2-en-1-ones and regio- and diastereospecifically construct highly enantiopure cyclopentanone-fused dihydrothiophenes that are otherwise difficult to prepare.

Authors

Cunzhi Chen
Jiayi Xu (ORCID: https://orcid.org/0000-0003-3465-7927)
Xinru Zhang (ORCID: https://orcid.org/0009-0002-5390-0566)
Zhanhui Yang

Institutions

Beijing University of Chemical Technology (CN)

Publication Details

Journal: Organic Letters
Published: 2026-02-16
DOI: https://doi.org/10.1021/acs.orglett.6c00306
Primary Topic: Catalytic C–H Functionalization Methods
Type: article
Field-Weighted Citation Impact: 0.00

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article

Enantioselective Access to Cyclopentanone-Fused Dihydrothiophenes

Cunzhi Chen, Jiayi Xu, Xinru Zhang, Zhanhui Yang

Feb 16, 2026

Organic Letters

Catalytic C–H Functionalization Methods

article

Enantioselective Access to Cyclopentanone-Fused Dihydrothiophenes

Cunzhi Chen, Jiayi Xu, Xinru Zhang, Zhanhui Yang

February 16, 2026article en

Abstract

Organic LettersVol. 28(8)

Beijing University of Chemical Technology (CN)

Openalex Percentile: Top 52%

Catalytic C–H Functionalization Methods

DOI Source OpenAlex

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Enantioselective Access to Cyclopentanone-Fused Dihydrothiophenes — Cunzhi Chen, Jiayi Xu, et al. · Organic Letters (2026) | TGRS Research Map | TGRS