Personalized reference intervals based on biological variation for serum bone turnover markers in healthy older adults
This study establishes BV-based prRI for BTMs in older adults, which offers a more clinically relevant interpretation of individual-level data than popRI and facilitates more accurate clinical decision-making.
Authors
- Runqing Mu (ORCID: https://orcid.org/0000-0001-5651-1086)
- Zihan Su (ORCID: https://orcid.org/0009-0008-6362-890X)
- Yusi Liu
- Dan Yang (ORCID: https://orcid.org/0000-0002-7347-7729)
- Hongyi Wang (ORCID: https://orcid.org/0000-0003-0189-3894)
- Ye Qin
- Lei Zhao
- Min Zhao
- Xu Wang
Institutions
- First Hospital of China Medical University (CN)
- China Medical University (CN)
Publication Details
- Journal
- Clinical Chemistry and Laboratory Medicine (CCLM)
- Published
- 2026-02-12
- DOI
- https://doi.org/10.1515/cclm-2025-1138
- Primary Topic
- Bone health and osteoporosis research
- Type
- article
- Field-Weighted Citation Impact
- 0.00