CD36-Mediated Fatty Acid Oxidation in CTCs Drives Immune Evasion and Metastasis in NSCLC
CD36<sup>+</sup> CTCs drive immune evasion and metastasis in PD-1-resistant NSCLC through FAO-dependent metabolic reprogramming. Targeting this metabolic vulnerability may enhance the efficacy of immunotherapy.
Authors
- Shuai Qian (ORCID: https://orcid.org/0009-0000-1671-2852)
- Fengping Wang (ORCID: https://orcid.org/0000-0002-2451-9769)
- Shuiyan Dai
- Huizhen Zhu
Institutions
- Zhejiang Chinese Medical University (CN)
- Wenzhou Medical University (CN)
- Quzhou City People's Hospital (CN)
Publication Details
- Journal
- Immunological Investigations
- Published
- 2026-02-16
- DOI
- https://doi.org/10.1080/08820139.2026.2619575
- Primary Topic
- Cancer, Lipids, and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.00