Case Report: Local anesthetic systemic toxicity during regional anesthesia in a patient with rheumatoid arthritis
Older patients with rheumatoid arthritis may be at increased risk for LAST due to disease-related vascular permeability changes, showing the need for increased vigilance during the administration of regional anesthesia. Early diagnosis and timely administration of intravenous lipid emulsion (ILE) remain critical for the successful management of this potentially life-threatening complication.
Authors
- Božana Obradović (ORCID: https://orcid.org/0000-0002-7978-2548)
- Danilo Obradović (ORCID: https://orcid.org/0000-0002-0171-0448)
- Relja Lukić (ORCID: https://orcid.org/0000-0003-3650-828X)
- Miodrag Milenović (ORCID: https://orcid.org/0000-0003-4062-3002)
- Misa Baic
Institutions
- University of Belgrade (RS)
- Institute of Orthopedics Banjica (RS)
- Centar za Promociju Nauke (RS)
- Institute for Migration Research (HR)
- Institute of Pharmacology (CZ)
- Resuscitation Council (GB)
Publication Details
- Journal
- Frontiers in Medicine
- Published
- 2026-02-16
- DOI
- https://doi.org/10.3389/fmed.2026.1758548
- Primary Topic
- Anesthesia and Pain Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00