Basal Luteinizing Hormone Combined with Age and BMI as a Simplified Screening Model for Central Precocious Puberty in Girls

A simplified screening model incorporating basal LH concentration, age, and BMI may serve as a practical initial screening tool to identify girls at higher risk of CPP and to reduce unnecessary GnRH stimulation testing. Prospective multicenter studies are required to validate the generalizability of this approach before broader clinical implementation.

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Publication Details

Journal
International Journal of Women s Health
Published
2026-02-01
DOI
https://doi.org/10.2147/ijwh.s583959
Primary Topic
Hypothalamic control of reproductive hormones
Type
article
Field-Weighted Citation Impact
0.00
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article

Basal Luteinizing Hormone Combined with Age and BMI as a Simplified Screening Model for Central Precocious Puberty in Girls

W. Li, Jiayu Li, Ziyi Yan, Y Li et al.
International Journal of Women s Health
Hypothalamic control of reproductive hormones
article

Basal Luteinizing Hormone Combined with Age and BMI as a Simplified Screening Model for Central Precocious Puberty in Girls

W. Li, Jiayu Li, Ziyi Yan, Y Li, Yali Cui, Jiaji Shuai, Tao Yu
article en

Abstract

A simplified screening model incorporating basal LH concentration, age, and BMI may serve as a practical initial screening tool to identify girls at higher risk of CPP and to reduce unnecessary GnRH stimulation testing. Prospective multicenter studies are required to validate the generalizability of this approach before broader clinical implementation.

International Journal of Women s HealthVol. Volume 18
Sichuan University (CN), Meizhou City People's Hospital (CN), West China Second University Hospital of Sichuan University (CN), Chengdu Women's and Children's Central Hospital (CN), Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital (CN)
Reduced inequalities
Openalex Percentile: Top 55%
Hypothalamic control of reproductive hormones
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Basal Luteinizing Hormone Combined with Age and BMI as a Simplified Screening Model for Central Precocious Puberty in Girls — W. Li, Jiayu Li, et al. · International Journal of Women s Health (2026) | TGRS Research Map | TGRS