Exploring estrogen synthesis and metabolism related markers and immune dynamics in osteoporosis-insights from single-cell RNA sequencing and Mendelian randomization
This study highlighted CCND1, DDIT4, and SCGB1A1 as markers for OP, supporting their involvement in disease progression and offering a foundation for targeted therapeutic strategies.
Authors
- Lizhen Lan
- Xiaoyun Hao
- Fei Xu
- Gang Sun
- Yu Wang
Institutions
- Shanxi Medical University (CN)
- First Hospital of Shanxi Medical University (CN)
Publication Details
- Journal
- Experimental Gerontology
- Published
- 2026-02-17
- DOI
- https://doi.org/10.1016/j.exger.2026.113070
- Primary Topic
- Single-cell and spatial transcriptomics
- Type
- article
- Field-Weighted Citation Impact
- 0.00