Resveratrol supplementation improves uterine immune resolution in mares susceptible to persistent breeding-induced endometritis

These findings demonstrate that resveratrol modulates specific components of the uterine inflammatory response in PBIE-susceptible mares. Such immunomodulatory effects may have relevance for improving reproductive efficiency, warranting further mechanistic and clinical investigation.

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Publication Details

Journal
Frontiers in Veterinary Science
Published
2026-02-16
DOI
https://doi.org/10.3389/fvets.2026.1760273
Primary Topic
Reproductive Physiology in Livestock
Type
article
Field-Weighted Citation Impact
0.00
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article

Resveratrol supplementation improves uterine immune resolution in mares susceptible to persistent breeding-induced endometritis

Chelsie Burden, Carleigh E. Fedorka, Pat McCue, Javier Funes et al.
Frontiers in Veterinary Science
Reproductive Physiology in Livestock
article

Resveratrol supplementation improves uterine immune resolution in mares susceptible to persistent breeding-induced endometritis

Chelsie Burden, Carleigh E. Fedorka, Pat McCue, Javier Funes, Patricio Razquin, I. Hamner, Jenn N. Hatzel, Jenny L. Sones, Jocelyn Howard, Lyta Foulk, Genevieve Denison
article en

Abstract

These findings demonstrate that resveratrol modulates specific components of the uterine inflammatory response in PBIE-susceptible mares. Such immunomodulatory effects may have relevance for improving reproductive efficiency, warranting further mechanistic and clinical investigation.

Frontiers in Veterinary ScienceVol. 13
Colorado State University (US)
Openalex Percentile: Top 51%
Reproductive Physiology in Livestock
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