Deletion of dltD gene modulates biofilm matrix and acid metabolism to attenuate Streptococcus mutans cariogenicity
These findings confirmed that <i>dltD</i> deletion attenuates <i>SM</i> cariogenicity by disrupting biofilm EPS and acid metabolism, supporting <i>dltD</i> as a potential target for caries prevention.
Authors
- Yijun Li (ORCID: https://orcid.org/0000-0001-8259-7522)
- Jingyi Huang (ORCID: https://orcid.org/0000-0002-1209-9699)
- Ling Zhan
- Shuai Chen (ORCID: https://orcid.org/0000-0002-8965-5876)
- Jingyun Du
- Xiaoyin Huang (ORCID: https://orcid.org/0009-0008-4760-7164)
- Zhoucheng Qiu
- Yujia Hao
- Shan Huang
Institutions
- Fujian Medical University (CN)
- Stomatology Hospital (CN)
- Fujian Provincial Hospital (CN)
Publication Details
- Journal
- Frontiers in Cellular and Infection Microbiology
- Published
- 2026-02-16
- DOI
- https://doi.org/10.3389/fcimb.2025.1741359
- Primary Topic
- Oral microbiology and periodontitis research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Natural Science Foundation of Fujian Province