Basi-Vertebral Nerve Ablation (BVNA): Part 1

Vertebrogenic pain due to degenerated or damaged vertebral endplates is a significant source of chronic low back pain.<sup>1</sup> The pathogenesis of vertebrogenic pain is attributed to the presence of endplates nociceptors that transmit afferent signals to the basivertebral nerve (BVN), located posteriorly within the vertebral body.<sup>2,3</sup> Chronic endplate inflammation triggers nociceptor proliferation, and associated chemical sensitization and mechanical stimulation leads to pain signals transmitted via the BVN and perceived as low back pain.<sup>1,2</sup> Therefore, radiofrequency ablation of the BVN has emerged as a potential minimally-invasive technique for management of vertebrogenic low back pain.<sup>4,5</sup> The thermal damage induced adjacent to the conducting region of the radiofrequency probe leads to interruption of pain transmission from vertebral endplates.<sup>5,6</sup> This video article gives an overview of the indications, procedural considerations, technical approach of basivertebral nerve ablation (BVNA), as well as post-procedure care and patient outcomes with representative clinical images obtained from our experience.

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Journal
American Journal of Neuroradiology
Published
2026-02-16
DOI
https://doi.org/10.3174/ajnr.a9242
Primary Topic
Spine and Intervertebral Disc Pathology
Type
article
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article

Basi-Vertebral Nerve Ablation (BVNA): Part 1

Sasicha Manupipatpong, Mona Gad, Jacob Schick, Majid Khan et al.
American Journal of Neuroradiology
Spine and Intervertebral Disc Pathology
article

Basi-Vertebral Nerve Ablation (BVNA): Part 1

Sasicha Manupipatpong, Mona Gad, Jacob Schick, Majid Khan, Rebecca Choi
article en

Abstract

Vertebrogenic pain due to degenerated or damaged vertebral endplates is a significant source of chronic low back pain.<sup>1</sup> The pathogenesis of vertebrogenic pain is attributed to the presence of endplates nociceptors that transmit afferent signals to the basivertebral nerve (BVN), located posteriorly within the vertebral body.<sup>2,3</sup> Chronic endplate inflammation triggers nociceptor proliferation, and associated chemical sensitization and mechanical stimulation leads to pain signals transmitted via the BVN and perceived as low back pain.<sup>1,2</sup> Therefore, radiofrequency ablation of the BVN has emerged as a potential minimally-invasive technique for management of vertebrogenic low back pain.<sup>4,5</sup> The thermal damage induced adjacent to the conducting region of the radiofrequency probe leads to interruption of pain transmission from vertebral endplates.<sup>5,6</sup> This video article gives an overview of the indications, procedural considerations, technical approach of basivertebral nerve ablation (BVNA), as well as post-procedure care and patient outcomes with representative clinical images obtained from our experience.

American Journal of Neuroradiology
Johns Hopkins University (US), Johns Hopkins Medicine (US)
Good health and well-being
Openalex Percentile: Top 55%
Spine and Intervertebral Disc Pathology
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Basi-Vertebral Nerve Ablation (BVNA): Part 1 — Sasicha Manupipatpong, Mona Gad, et al. · American Journal of Neuroradiology (2026) | TGRS Research Map | TGRS