Basi-Vertebral Nerve Ablation (BVNA): Part 1
Vertebrogenic pain due to degenerated or damaged vertebral endplates is a significant source of chronic low back pain.<sup>1</sup> The pathogenesis of vertebrogenic pain is attributed to the presence of endplates nociceptors that transmit afferent signals to the basivertebral nerve (BVN), located posteriorly within the vertebral body.<sup>2,3</sup> Chronic endplate inflammation triggers nociceptor proliferation, and associated chemical sensitization and mechanical stimulation leads to pain signals transmitted via the BVN and perceived as low back pain.<sup>1,2</sup> Therefore, radiofrequency ablation of the BVN has emerged as a potential minimally-invasive technique for management of vertebrogenic low back pain.<sup>4,5</sup> The thermal damage induced adjacent to the conducting region of the radiofrequency probe leads to interruption of pain transmission from vertebral endplates.<sup>5,6</sup> This video article gives an overview of the indications, procedural considerations, technical approach of basivertebral nerve ablation (BVNA), as well as post-procedure care and patient outcomes with representative clinical images obtained from our experience.
Authors
- Sasicha Manupipatpong (ORCID: https://orcid.org/0000-0001-7530-3186)
- Mona Gad (ORCID: https://orcid.org/0000-0002-0981-0806)
- Jacob Schick
- Majid Khan
- Rebecca Choi
Institutions
- Johns Hopkins University (US)
- Johns Hopkins Medicine (US)
Publication Details
- Journal
- American Journal of Neuroradiology
- Published
- 2026-02-16
- DOI
- https://doi.org/10.3174/ajnr.a9242
- Primary Topic
- Spine and Intervertebral Disc Pathology
- Type
- article
- Field-Weighted Citation Impact
- 0.00