Zenodo Data Sharing User Story: When Lab Adaptation Skews the Data: Sharing Gonorrhea Genomes
User story showcasing a real-world researcher's experience with data sharing in the Zenodo repository. This case study shows how Prism, Northwestern University Feinberg School of Medicine's InvenioRDM‑powered repository, supports transparent genomic research through the work of Iryna Boiko, Selma Metaane, and Hank Seifert. By analyzing more than 15,000 Neisseria gonorrhoeae genomes, the team uncovered that many publicly available sequences reflect lab‑adapted, nonpiliated variants. Sharing their raw data, Python and R scripts, and protocols through Prism ensures long‑term reuse, supports NIH compliance, and enables researchers studying other pathogens to better detect and address cultivation bias. Zenodo GREI User Stories are supported by the National Institutes of Health (NIH) Office of Data Science Strategy/Office of the NIH Director pursuant to OTA-21-009, “Generalist Repository Ecosystem Initiative (GREI)” through through Other Transactions Agreement (OTA) Number 1OT2DB000013.
Authors
- Lars Holm Nielsen (ORCID: https://orcid.org/0000-0001-8135-3489)
- Matthew B. Carson (ORCID: https://orcid.org/0000-0003-4105-9220)
- Pablo Tamarit
- Nicola Tarocco
- Sara Gonzales
- Pearl Go
- Jose Benito Gonzalez Lopez
- Kristi Holmes
Institutions
- Northwestern University (PH)
- European Organization for Nuclear Research (CH)
Publication Details
- Journal
- Zenodo (CERN European Organization for Nuclear Research)
- Published
- 2026-01-12
- DOI
- https://doi.org/10.5281/zenodo.18662618
- Primary Topic
- Bacterial Infections and Vaccines
- Type
- article
- Field-Weighted Citation Impact
- 0.00