Zenodo Data Sharing User Story: When Lab Adaptation Skews the Data: Sharing Gonorrhea Genomes

User story showcasing a real-world researcher's experience with data sharing in the Zenodo repository. This case study shows how Prism, Northwestern University Feinberg School of Medicine's InvenioRDM‑powered repository, supports transparent genomic research through the work of Iryna Boiko, Selma Metaane, and Hank Seifert. By analyzing more than 15,000 Neisseria gonorrhoeae genomes, the team uncovered that many publicly available sequences reflect lab‑adapted, nonpiliated variants. Sharing their raw data, Python and R scripts, and protocols through Prism ensures long‑term reuse, supports NIH compliance, and enables researchers studying other pathogens to better detect and address cultivation bias. Zenodo GREI User Stories are supported by the National Institutes of Health (NIH) Office of Data Science Strategy/Office of the NIH Director pursuant to OTA-21-009, “Generalist Repository Ecosystem Initiative (GREI)” through through Other Transactions Agreement (OTA) Number 1OT2DB000013.

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Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2026-01-12
DOI
https://doi.org/10.5281/zenodo.18662618
Primary Topic
Bacterial Infections and Vaccines
Type
article
Field-Weighted Citation Impact
0.00
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article

Zenodo Data Sharing User Story: When Lab Adaptation Skews the Data: Sharing Gonorrhea Genomes

Lars Holm Nielsen, Matthew B. Carson, Pablo Tamarit, Nicola Tarocco et al.
Zenodo (CERN European Organization for Nuclear Research)
Bacterial Infections and Vaccines
article

Zenodo Data Sharing User Story: When Lab Adaptation Skews the Data: Sharing Gonorrhea Genomes

Lars Holm Nielsen, Matthew B. Carson, Pablo Tamarit, Nicola Tarocco, Sara Gonzales, Pearl Go, Jose Benito Gonzalez Lopez, Kristi Holmes
article en

Abstract

User story showcasing a real-world researcher's experience with data sharing in the Zenodo repository. This case study shows how Prism, Northwestern University Feinberg School of Medicine's InvenioRDM‑powered repository, supports transparent genomic research through the work of Iryna Boiko, Selma Metaane, and Hank Seifert. By analyzing more than 15,000 Neisseria gonorrhoeae genomes, the team uncovered that many publicly available sequences reflect lab‑adapted, nonpiliated variants. Sharing their raw data, Python and R scripts, and protocols through Prism ensures long‑term reuse, supports NIH compliance, and enables researchers studying other pathogens to better detect and address cultivation bias. Zenodo GREI User Stories are supported by the National Institutes of Health (NIH) Office of Data Science Strategy/Office of the NIH Director pursuant to OTA-21-009, “Generalist Repository Ecosystem Initiative (GREI)” through through Other Transactions Agreement (OTA) Number 1OT2DB000013.

Zenodo (CERN European Organization for Nuclear Research)
Northwestern University (PH), European Organization for Nuclear Research (CH)
Openalex Percentile: Top 53%
Bacterial Infections and Vaccines
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