Developments in the therapeutic landscape for dry eye

The evolving understanding of DED supports a shift toward mechanism-based, personalized management that addresses inflammation, tear film instability, neurosensory dysfunction, and glandular insufficiency. Integrating targeted therapies, device-based interventions, and regenerative approaches with improved diagnostics may enable more predictable, proactive care. Rigorous research is still needed to optimize treatment selection and sequencing.

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Publication Details

Journal
Expert Opinion on Pharmacotherapy
Published
2026-01-22
DOI
https://doi.org/10.1080/14656566.2026.2633382
Primary Topic
Ocular Surface and Contact Lens
Type
article
Field-Weighted Citation Impact
0.00
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article

Developments in the therapeutic landscape for dry eye

Giuseppe Giannaccare, Vincenzo Scorcia, Giulia Coco, Andrea Lucisano et al.
Expert Opinion on Pharmacotherapy
Ocular Surface and Contact Lens
article

Developments in the therapeutic landscape for dry eye

Giuseppe Giannaccare, Vincenzo Scorcia, Giulia Coco, Andrea Lucisano, Linda Marie Louise Busin, Massimiliano Borselli, Costanza Rossi
article en

Abstract

The evolving understanding of DED supports a shift toward mechanism-based, personalized management that addresses inflammation, tear film instability, neurosensory dysfunction, and glandular insufficiency. Integrating targeted therapies, device-based interventions, and regenerative approaches with improved diagnostics may enable more predictable, proactive care. Rigorous research is still needed to optimize treatment selection and sequencing.

Expert Opinion on PharmacotherapyVol. 27(2)
University of Rome Tor Vergata (IT), University of Cagliari (IT), Magna Graecia University (IT), Fatebenefratelli Hospital (IT)
Openalex Percentile: Top 57%
Ocular Surface and Contact Lens
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