Diabetes Mellitus Facilitates Gallstone Formation Through CXCR2‐NETs–Mediated Liver‐Bile Barrier Damage
Diabetes promotes NETs formation through CXCR2 activation, which damages the liver-bile barrier and facilitates gallstone development. Sarcosine may serve as a potential therapeutic agent, providing a theoretical basis for clinical intervention.
Authors
- Xue Db
- Ziang Meng
- Yi Zheng (ORCID: https://orcid.org/0000-0002-5230-0254)
- Bing Zhang (ORCID: https://orcid.org/0000-0002-9725-2524)
- Chao Shi (ORCID: https://orcid.org/0000-0003-2347-6127)
- Shuo Feng (ORCID: https://orcid.org/0000-0001-9552-5018)
- Wang Tong
- Xianzhi Meng
- Zhenghao Huang
- T Liu
- Biao Ma
Institutions
- Harbin Medical University (CN)
- First Affiliated Hospital of Harbin Medical University (CN)
Publication Details
- Journal
- Advanced Science
- Published
- 2026-02-16
- DOI
- https://doi.org/10.1002/advs.202519500
- Primary Topic
- Gallbladder and Bile Duct Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00