Diagnosis and treatment strategies for cardiogenic shock in Takotsubo syndrome with a temporary left ventricular assist device—A single-center study

This retrospective single-center study on the use of MCS in TTS management supports results from previous studies reporting on the benefit of Impella therapy. Our experience shows that Impella support provides stabilization of CS and unloading of the left ventricle, allowing full recovery of left ventricular function and reversing TTS findings. For patients who do not adequately respond to Impella support alone, escalation to a combination of Impella and extracorporeal membrane oxygenation strategy is feasible to further improve cardiac output, while protecting the left ventricle from the increased afterload<b>.</b>

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Publication Details

Journal
JHLT Open
Published
2026-02-16
DOI
https://doi.org/10.1016/j.jhlto.2026.100520
Primary Topic
Takotsubo Cardiomyopathy and Associated Phenomena
Type
article
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article

Diagnosis and treatment strategies for cardiogenic shock in Takotsubo syndrome with a temporary left ventricular assist device—A single-center study

Anna Huang, Leonhard Wert, Jasper Iske, Cheng‐Ying Chiu et al.
JHLT Open
Takotsubo Cardiomyopathy and Associated Phenomena
article

Diagnosis and treatment strategies for cardiogenic shock in Takotsubo syndrome with a temporary left ventricular assist device—A single-center study

Anna Huang, Leonhard Wert, Jasper Iske, Cheng‐Ying Chiu, Stephan Jacobs, Julius Kaemmel, Carla L. Schuering, Vanessa I.T. Zwaans, Johanna K.R. Von Mackensen, Leonard Pitts, Christoph T. Starck, Volkmar Falk, Gaik Nersesian, Evgenij V. Potapov
article en

Abstract

This retrospective single-center study on the use of MCS in TTS management supports results from previous studies reporting on the benefit of Impella therapy. Our experience shows that Impella support provides stabilization of CS and unloading of the left ventricle, allowing full recovery of left ventricular function and reversing TTS findings. For patients who do not adequately respond to Impella support alone, escalation to a combination of Impella and extracorporeal membrane oxygenation strategy is feasible to further improve cardiac output, while protecting the left ventricle from the increased afterload<b>.</b>

JHLT OpenVol. 12
ETH Zurich (CH), Humboldt-Universität zu Berlin (DE), Deutsches Herzzentrum der Charité (DE), German Centre for Cardiovascular Research (DE), Deutsches Herzzentrum München (DE), Berlin Heart (Germany) (DE)
Good health and well-being
Openalex Percentile: Top 57%
Takotsubo Cardiomyopathy and Associated Phenomena
DOIOpen Access PDFOpenAlex
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Diagnosis and treatment strategies for cardiogenic shock in Takotsubo syndrome with a temporary left ventricular assist device—A single-center study — Anna Huang, Leonhard Wert, et al. · JHLT Open (2026) | TGRS Research Map | TGRS