Patterns of Comorbidity Between Chronic Pain and Chronic Diseases in US Adults: A Cross-Sectional Analysis of NHANES Data

Chronic pain, as a comorbid factor, should be integrated into the management of chronic diseases. Clinical practice should prioritize synergistic prevention strategies, such as smoking cessation interventions, to reduce both pain and comorbidity risks. To better understand the causal relationships between chronic pain and chronic diseases, future studies should focus on longitudinal designs and include objective pain measures, such as biomarkers.

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Publication Details

Journal
Journal of Pain Research
Published
2026-02-01
DOI
https://doi.org/10.2147/jpr.s555970
Primary Topic
Musculoskeletal pain and rehabilitation
Type
article
Field-Weighted Citation Impact
0.00

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article

Patterns of Comorbidity Between Chronic Pain and Chronic Diseases in US Adults: A Cross-Sectional Analysis of NHANES Data

Guozhong Zhou, Chao Song, Wei Yang, Rong Wang et al.
Journal of Pain Research
Musculoskeletal pain and rehabilitation
article

Patterns of Comorbidity Between Chronic Pain and Chronic Diseases in US Adults: A Cross-Sectional Analysis of NHANES Data

Guozhong Zhou, Chao Song, Wei Yang, Rong Wang, Yan Dong, Xuesong Chen, Shunli Cai, Fusong Yang, Hua Yang
article en

Abstract

Chronic pain, as a comorbid factor, should be integrated into the management of chronic diseases. Clinical practice should prioritize synergistic prevention strategies, such as smoking cessation interventions, to reduce both pain and comorbidity risks. To better understand the causal relationships between chronic pain and chronic diseases, future studies should focus on longitudinal designs and include objective pain measures, such as biomarkers.

Journal of Pain ResearchVol. Volume 19
Kunming University of Science and Technology (CN), Kunming Medical University (CN), First People's Hospital of Yunnan Province (CN), First Affiliated Hospital of Kunming Medical University (CN)
Kunming University of Science and Technology
Good health and well-being
Openalex Percentile: Top 54%
Musculoskeletal pain and rehabilitation
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Patterns of Comorbidity Between Chronic Pain and Chronic Diseases in US Adults: A Cross-Sectional Analysis of NHANES Data — Guozhong Zhou, Chao Song, et al. · Journal of Pain Research (2026) | TGRS Research Map | TGRS