Multimorbidity patterns are associated with postoperative delirium in older patients undergoing non-cardiac surgery: an observational study
We identified a specific pattern of multimorbidities significantly associated with frailty, cognitive impairment, and POD risk. The high-risk subgroup's effect on POD was partially mediated by frailty. Multinomial logistic regression model accurately predicted subgroup membership, offering a potential tool for preoperative risk stratification.
Authors
- GU Han-wen
- Di Fan
- Jie Yang (ORCID: https://orcid.org/0000-0003-4801-7162)
- Xiaoyi Hu (ORCID: https://orcid.org/0000-0002-2786-4234)
- Xueyan Guo
- Mu-Huo Ji
Institutions
- Second Affiliated Hospital of Nanjing Medical University (CN)
- First Affiliated Hospital of Zhengzhou University (CN)
Publication Details
- Journal
- Frontiers in Medicine
- Published
- 2026-02-16
- DOI
- https://doi.org/10.3389/fmed.2026.1742763
- Primary Topic
- Intensive Care Unit Cognitive Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China