18F-FDG PETCT in a Patient With Succinate Dehydrogenase-Deficient Renal Cell Carcinoma

A 32-year-old man presented with a left renal mass incidentally found during a recent health examination. Renal cell carcinoma was highly suspected by the subsequent abdominal enhanced CT scan. The renal tumor exhibited extremely intense 18F-FDG uptake on the 18F-FDG PET/CT. Radical nephrectomy was performed, and the diagnosis of succinate dehydrogenase (SDH)-deficient renal cell carcinoma (SDH-deficient RCC) was confirmed by the histopathology and genetic analysis.

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Publication Details

Journal
Clinical Nuclear Medicine
Published
2026-02-04
DOI
https://doi.org/10.1097/rlu.0000000000006368
Primary Topic
Renal cell carcinoma treatment
Type
article
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article

18F-FDG PETCT in a Patient With Succinate Dehydrogenase-Deficient Renal Cell Carcinoma

Zhanli Fu, Xueqi Chen, Caixia Wu, Wuning Du
Clinical Nuclear Medicine
Renal cell carcinoma treatment
article

18F-FDG PETCT in a Patient With Succinate Dehydrogenase-Deficient Renal Cell Carcinoma

Zhanli Fu, Xueqi Chen, Caixia Wu, Wuning Du
article en

Abstract

A 32-year-old man presented with a left renal mass incidentally found during a recent health examination. Renal cell carcinoma was highly suspected by the subsequent abdominal enhanced CT scan. The renal tumor exhibited extremely intense 18F-FDG uptake on the 18F-FDG PET/CT. Radical nephrectomy was performed, and the diagnosis of succinate dehydrogenase (SDH)-deficient renal cell carcinoma (SDH-deficient RCC) was confirmed by the histopathology and genetic analysis.

Clinical Nuclear Medicine
Peking University (CN), Weihai Municipal Hospital (CN), Peking University First Hospital (CN)
Good health and well-being
Openalex Percentile: Top 54%
Renal cell carcinoma treatment
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