In silico interaction analysis of selected natural compounds with bacteriophage-encoded hyaluronate lyase from Streptococcus pyogenes

These findings suggest that these natural product scaffolds are promising anti-virulence leads that may limit <i>S. pyogenes</i> tissue invasion while minimizing selective pressure for resistance development.

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Publication Details

Journal
Frontiers in Medicine
Published
2026-02-16
DOI
https://doi.org/10.3389/fmed.2026.1709023
Primary Topic
Bacteriophages and microbial interactions
Type
article
Field-Weighted Citation Impact
0.00

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article

In silico interaction analysis of selected natural compounds with bacteriophage-encoded hyaluronate lyase from Streptococcus pyogenes

Samia S. Alkhalil
Frontiers in Medicine
Bacteriophages and microbial interactions
article

In silico interaction analysis of selected natural compounds with bacteriophage-encoded hyaluronate lyase from Streptococcus pyogenes

Samia S. Alkhalil
article en

Abstract

These findings suggest that these natural product scaffolds are promising anti-virulence leads that may limit <i>S. pyogenes</i> tissue invasion while minimizing selective pressure for resistance development.

Frontiers in MedicineVol. 13
Shaqra University (SA)
Shaqra University
Affordable and clean energy
Openalex Percentile: Top 59%
Bacteriophages and microbial interactions
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In silico interaction analysis of selected natural compounds with bacteriophage-encoded hyaluronate lyase from Streptococcus pyogenes — Samia S. Alkhalil · Frontiers in Medicine (2026) | TGRS Research Map | TGRS