Post-COVID fatigue disproportionately affects women: evidence from the DEFEAT Corona cohort

Our findings demonstrate significant gender-based differences in fatigue-related symptoms in PCS, with women experiencing both higher prevalence and severity, and menstrual cycle associated symptom worsening. These results highlight the importance of sex and gender-specific approaches to understanding and managing PCS-related fatigue, with implications for clinical care and future research directions.

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Publication Details

Journal
Frontiers in Public Health
Published
2026-02-16
DOI
https://doi.org/10.3389/fpubh.2026.1755106
Primary Topic
Long-Term Effects of COVID-19
Type
article
Field-Weighted Citation Impact
0.00

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article

Post-COVID fatigue disproportionately affects women: evidence from the DEFEAT Corona cohort

Marie Mikuteit, Frank Klawonn, C Happle, Viktoria Lampe et al.
Frontiers in Public Health
Long-Term Effects of COVID-19
article

Post-COVID fatigue disproportionately affects women: evidence from the DEFEAT Corona cohort

Marie Mikuteit, Frank Klawonn, C Happle, Viktoria Lampe, Georg M N Behrens, Tim Riester, Andrea Stölting, Theresa Thölking, Frank Müller, Sandra Steffens, Karolin Beinhauer, Lena-Marie Theil, Dominik Schröder, Imke Von Wasielewski, Mareike Meier-Maiwald
article en

Abstract

Our findings demonstrate significant gender-based differences in fatigue-related symptoms in PCS, with women experiencing both higher prevalence and severity, and menstrual cycle associated symptom worsening. These results highlight the importance of sex and gender-specific approaches to understanding and managing PCS-related fatigue, with implications for clinical care and future research directions.

Frontiers in Public HealthVol. 14
Ostfalia University of Applied Sciences (DE), Medizinische Hochschule Hannover (DE), Universitätsmedizin Göttingen (DE), German Center for Lung Research (DE), University of Göttingen (DE), Michigan State University (US)
Pfizer, Niedersächsisches Ministerium für Wissenschaft und Kultur, European Regional Development Fund
No poverty
Openalex Percentile: Top 58%
Long-Term Effects of COVID-19
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