Biomarkers for feeding intolerance in infants with complex heart defects undergoing palliation surgery

We suggest that, when measured sequentially, plasma levels of I-FABP and claudin-3 may help to predict children with CHD at risk of feeding intolerance post cardiac surgery. If further validated in larger cohort, these biomarkers may aid in optimizing feeding protocols aimed at reducing sequelae such as NEC.

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Publication Details

Journal
Journal of Pediatric Gastroenterology and Nutrition
Published
2026-02-16
DOI
https://doi.org/10.1002/jpn3.70377
Primary Topic
Infant Nutrition and Health
Type
article
Field-Weighted Citation Impact
0.00

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article

Biomarkers for feeding intolerance in infants with complex heart defects undergoing palliation surgery

Supriya Nair, Y. Liu, Katarzyna Bigaj, Alvaro Coronado Muñoz et al.
Journal of Pediatric Gastroenterology and Nutrition
Infant Nutrition and Health
article

Biomarkers for feeding intolerance in infants with complex heart defects undergoing palliation surgery

Supriya Nair, Y. Liu, Katarzyna Bigaj, Alvaro Coronado Muñoz, Pediatric Gastroenterology–PICU–Cardiac Surgery Study Group
article en

Abstract

We suggest that, when measured sequentially, plasma levels of I-FABP and claudin-3 may help to predict children with CHD at risk of feeding intolerance post cardiac surgery. If further validated in larger cohort, these biomarkers may aid in optimizing feeding protocols aimed at reducing sequelae such as NEC.

Journal of Pediatric Gastroenterology and Nutrition
Children's Hospital at Montefiore (US), The University of Texas Health Science Center (US)
University of Texas Health Science Center at Houston, McGovern Medical School
Openalex Percentile: Top 53%
Infant Nutrition and Health
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