Lactobacillus rhamnosus MY-1 alleviates deoxynivalenol-induced oxidative stress, inflammation, and gut microbiota dysbiosis both in vivo and in vitro

This study demonstrates that <i>Lactobacillus rhamnosus</i> MY-1 exerts comprehensive protective effects against DON-induced intestinal toxicity through integrated mechanisms, including direct detoxification, antioxidant and anti-inflammatory activities, and microbiota modulation. These findings underscore the value of MY-1 as a well-characterized probiotic candidate for mitigating mycotoxin effects in animal production.

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Publication Details

Journal
Frontiers in Microbiology
Published
2026-02-16
DOI
https://doi.org/10.3389/fmicb.2026.1750402
Primary Topic
Mycotoxins in Agriculture and Food
Type
article
Field-Weighted Citation Impact
0.00

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article

Lactobacillus rhamnosus MY-1 alleviates deoxynivalenol-induced oxidative stress, inflammation, and gut microbiota dysbiosis both in vivo and in vitro

Zuhua Yu, Rongxian Guo, Yukai Lin, Bo Wen et al.
Frontiers in Microbiology
Mycotoxins in Agriculture and Food
article

Lactobacillus rhamnosus MY-1 alleviates deoxynivalenol-induced oxidative stress, inflammation, and gut microbiota dysbiosis both in vivo and in vitro

Zuhua Yu, Rongxian Guo, Yukai Lin, Bo Wen, Chengshui Liao, Ke Ding, Ruibiao Wang, Jie Yao, Hanqing Zhao, Lei Wang, Xiaojing Xia, Yanzhao Xu
article en

Abstract

This study demonstrates that <i>Lactobacillus rhamnosus</i> MY-1 exerts comprehensive protective effects against DON-induced intestinal toxicity through integrated mechanisms, including direct detoxification, antioxidant and anti-inflammatory activities, and microbiota modulation. These findings underscore the value of MY-1 as a well-characterized probiotic candidate for mitigating mycotoxin effects in animal production.

Frontiers in MicrobiologyVol. 17
Henan University of Science and Technology (CN), Henan Institute of Science and Technology (CN)
National Natural Science Foundation of China
Openalex Percentile: Top 54%
Mycotoxins in Agriculture and Food
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