Lactobacillus rhamnosus MY-1 alleviates deoxynivalenol-induced oxidative stress, inflammation, and gut microbiota dysbiosis both in vivo and in vitro
This study demonstrates that <i>Lactobacillus rhamnosus</i> MY-1 exerts comprehensive protective effects against DON-induced intestinal toxicity through integrated mechanisms, including direct detoxification, antioxidant and anti-inflammatory activities, and microbiota modulation. These findings underscore the value of MY-1 as a well-characterized probiotic candidate for mitigating mycotoxin effects in animal production.
Authors
- Zuhua Yu
- Rongxian Guo (ORCID: https://orcid.org/0000-0003-0206-3729)
- Yukai Lin
- Bo Wen (ORCID: https://orcid.org/0000-0002-3839-2391)
- Chengshui Liao
- Ke Ding
- Ruibiao Wang
- Jie Yao
- Hanqing Zhao
- Lei Wang
- Xiaojing Xia
- Yanzhao Xu
Institutions
- Henan University of Science and Technology (CN)
- Henan Institute of Science and Technology (CN)
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2026-02-16
- DOI
- https://doi.org/10.3389/fmicb.2026.1750402
- Primary Topic
- Mycotoxins in Agriculture and Food
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China