Clinicopathological and Genomic Analysis of SMARCA4-Deficient Non-Small Cell Lung Cancer: A Retrospective Cohort Study

<i>SMARCA4</i>-dNSCLC represents a distinct clinicopathologic entity with poor outcomes. Given the aggressive nature and poor prognosis of untreated <i>SMARCA4</i>-dNSCLC, timely diagnosis and multimodal treatment are essential to improving survival. Further prospective studies are needed to optimize management strategies.

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Publication Details

Journal
Cancer Management and Research
Published
2026-02-01
DOI
https://doi.org/10.2147/cmar.s565394
Primary Topic
Chromatin Remodeling and Cancer
Type
article
Field-Weighted Citation Impact
0.00
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article

Clinicopathological and Genomic Analysis of SMARCA4-Deficient Non-Small Cell Lung Cancer: A Retrospective Cohort Study

Diming Wang, Chi Zhang, Qingming Shi, Dongmei Chen et al.
Cancer Management and Research
Chromatin Remodeling and Cancer
article

Clinicopathological and Genomic Analysis of SMARCA4-Deficient Non-Small Cell Lung Cancer: A Retrospective Cohort Study

Diming Wang, Chi Zhang, Qingming Shi, Dongmei Chen, Wei Ye, Sihan Wu, Heng Zhang
article en

Abstract

<i>SMARCA4</i>-dNSCLC represents a distinct clinicopathologic entity with poor outcomes. Given the aggressive nature and poor prognosis of untreated <i>SMARCA4</i>-dNSCLC, timely diagnosis and multimodal treatment are essential to improving survival. Further prospective studies are needed to optimize management strategies.

Cancer Management and ResearchVol. Volume 18
Anhui Provincial Hospital (CN)
No poverty
Openalex Percentile: Top 54%
Chromatin Remodeling and Cancer
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