Genetic susceptibility to heat identifies rare neurological diseases at particular risk from climate change impacts
Genetic variation may generate latent phenotypes that manifest only at elevated ambient temperatures, with some neurological disease groups being highlighted. This is an exploratory study. Identifying more calortypic variants will help uncover the full spectrum of human genetic vulnerability to climate change impacts.
Authors
- Helena Martins (ORCID: https://orcid.org/0000-0001-8430-0446)
- Angeliki Vakrinou (ORCID: https://orcid.org/0000-0003-4363-468X)
- Ravishankara Bellampalli (ORCID: https://orcid.org/0009-0009-9845-1056)
- Alessia Romagnolo (ORCID: https://orcid.org/0000-0001-5357-0961)
- James D. Mills (ORCID: https://orcid.org/0000-0002-9910-2933)
- Susanna Pagni
- Till S. Zimmer (ORCID: https://orcid.org/0000-0002-6869-3697)
- Medine Idrizoglu Gulcebi
- Sisodiya Sm
- Patrick Moloney
- Eleonora Aronica
Institutions
- Cornell University (US)
- Epilepsy Research UK (GB)
- MIND Research Institute (US)
- Amsterdam Neuroscience (NL)
- Weill Cornell Medicine (US)
- University College London (GB)
- Epilepsy Society (GB)
Publication Details
- Journal
- Journal of Neurology Neurosurgery & Psychiatry
- Published
- 2026-02-16
- DOI
- https://doi.org/10.1136/jnnp-2025-337077
- Primary Topic
- Climate Change and Health Impacts
- Type
- article
- Field-Weighted Citation Impact
- 0.00