Pretransplant CMV-IgG Titers and DNAemia Are Associated With CMV Infections Post Allogeneic Hematopoietic Cell Transplant With or Without Letermovir
Pretransplant high CMV-IgG-titers and detectable/quantifiable DNAemia were associated with higher posttransplant csCMVi/CMV-DNAemia incidence, including in the letermovir era. Additional studies on the clinical utility of baseline pretransplant CMV burden in CMV prophylaxis stratification algorithms are needed.
Authors
- Léna Royston (ORCID: https://orcid.org/0000-0003-2367-7682)
- Amandine Pradier
- Manuel Schibler
- Sarah Morin (ORCID: https://orcid.org/0009-0003-5740-2035)
- Laurent Kaiser (ORCID: https://orcid.org/0000-0002-0857-2252)
- Federica Giannotti
- Federico Simonetta (ORCID: https://orcid.org/0000-0002-0399-689X)
- Anne-Claire Mamez
- Stavroula Masouridi-Levrat
- Ming Zou
- Christian Van Delden
Institutions
- University of Geneva (CH)
- Hospital Base (CL)
- University Hospital of Geneva (CH)
- Geneva College (US)
Publication Details
- Journal
- Open Forum Infectious Diseases
- Published
- 2026-02-01
- DOI
- https://doi.org/10.1093/ofid/ofag068
- Primary Topic
- Cytomegalovirus and herpesvirus research
- Type
- article
- Field-Weighted Citation Impact
- 0.00