Effects of Lung-Protective Ventilation on Cerebral Oxygenation During One-Lung Ventilation in Neonates

Despite maintaining SpO<sub>2</sub> within the normal range, rSO<sub>2</sub> declined during OLV in neonates. The application of permissive hypercapnia during OLV improved rSO<sub>2</sub> within a certain range. Routine perioperative monitoring of rSO<sub>2</sub> in neonates undergoing OLV may facilitate early detection of cerebral oxygenation changes, contributing to neuroprotection.

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Publication Details

Journal
Journal of Pain Research
Published
2026-02-01
DOI
https://doi.org/10.2147/jpr.s559083
Primary Topic
Respiratory Support and Mechanisms
Type
article
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article

Effects of Lung-Protective Ventilation on Cerebral Oxygenation During One-Lung Ventilation in Neonates

Jinwei Duan, Yunwei Wei, Jinbao Ren, Lei Lv et al.
Journal of Pain Research
Respiratory Support and Mechanisms
article

Effects of Lung-Protective Ventilation on Cerebral Oxygenation During One-Lung Ventilation in Neonates

Jinwei Duan, Yunwei Wei, Jinbao Ren, Lei Lv, Hong-Peng Zhang, Wei-Zhi Zhang
article en

Abstract

Despite maintaining SpO<sub>2</sub> within the normal range, rSO<sub>2</sub> declined during OLV in neonates. The application of permissive hypercapnia during OLV improved rSO<sub>2</sub> within a certain range. Routine perioperative monitoring of rSO<sub>2</sub> in neonates undergoing OLV may facilitate early detection of cerebral oxygenation changes, contributing to neuroprotection.

Journal of Pain ResearchVol. Volume 19
Shanxi Medical University (CN), Shanxi Provincial Children's Hospital (CN), Shanxi Provincial People’s Hospital (CN)
Clean water and sanitation
Openalex Percentile: Top 55%
Respiratory Support and Mechanisms
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