A Prognostic Model Based on Immune–Inflammatory–Nutritional Indicators for 28-Day Mortality in Sepsis Patients with Acute-on-Chronic Liver Failure

We have successfully developed and validated a robust nomogram that utilizes routinely available immune-inflammatory-nutritional indicators to provide individualized risk estimation of 28-day mortality in sepsis patients with ACLF. This model represents an advanced prognostic instrument when compared to traditional scoring systems, with the potential to enable early detection of high-risk patients and inform individualized therapeutic interventions.