Acute myocardial infarction caused by coronary tumor embolism from uterine leiomyosarcoma: a case report

While most AMI events result from thrombotic occlusion and respond to anticoagulation, tumor emboli require mechanical intervention. Aspiration thrombectomy proved effective in this case. Clinicians should recognize that tumor embolism can induce AMI even in previously unreported cancer types, as pulmonary metastases may invade the pulmonary veins enabling tumor fragments to enter systemic circulation. Early recognition and intervention are critical for survival in these patients. Tumor embolism should be considered in the differential diagnosis of patients with cancer presenting with unexplained chest pain or dyspnea.

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Publication Details

Journal
Gynecologic Oncology Reports
Published
2026-02-16
DOI
https://doi.org/10.1016/j.gore.2026.102047
Primary Topic
Cardiac tumors and thrombi
Type
article
Field-Weighted Citation Impact
0.00
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article

Acute myocardial infarction caused by coronary tumor embolism from uterine leiomyosarcoma: a case report

Kohei Tamura, Yuji Takei, Yoshifumi Takahashi, Akiyo Taneichi et al.
Gynecologic Oncology Reports
Cardiac tumors and thrombi
article

Acute myocardial infarction caused by coronary tumor embolism from uterine leiomyosarcoma: a case report

Kohei Tamura, Yuji Takei, Yoshifumi Takahashi, Akiyo Taneichi, Takahiro Koyanagi, Miki Shinohara, Hiroyuki Fujiwara, Yumi Shirasu
article en

Abstract

While most AMI events result from thrombotic occlusion and respond to anticoagulation, tumor emboli require mechanical intervention. Aspiration thrombectomy proved effective in this case. Clinicians should recognize that tumor embolism can induce AMI even in previously unreported cancer types, as pulmonary metastases may invade the pulmonary veins enabling tumor fragments to enter systemic circulation. Early recognition and intervention are critical for survival in these patients. Tumor embolism should be considered in the differential diagnosis of patients with cancer presenting with unexplained chest pain or dyspnea.

Gynecologic Oncology ReportsVol. 64
Jichi Medical University (JP)
Good health and well-being
Openalex Percentile: Top 57%
Cardiac tumors and thrombi
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Acute myocardial infarction caused by coronary tumor embolism from uterine leiomyosarcoma: a case report — Kohei Tamura, Yuji Takei, et al. · Gynecologic Oncology Reports (2026) | TGRS Research Map | TGRS