The Prognostic Value of Dynamic Changes in Prognostic Nutritional Index (PNI) During Treatment in Lung Cancer: Is Improvement a Better Predictor than Baseline?

This study demonstrates that the PNI is not merely a static baseline marker but also a dynamic biomarker that reflects the host's response to treatment and disease. An increase in PNI values during treatment is associated with improved survival, suggesting that dynamic monitoring of nutritional and immune status provides valuable prognostic information for patient management in lung cancer patients.