Haematological Profile of Patients with Sickle Cell Disease in the Acholi Sub-Region, Uganda

In patients with sickle cell disease, there were increased white blood cells, platelets, and low red blood cells. That may reflect increased haemolytic activities that destroy the sickled red blood cells in low oxygen tension. Hydroxyurea use was associated with normal platelet counts.

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Publication Details

Journal
Journal of Blood Medicine
Published
2026-02-01
DOI
https://doi.org/10.2147/jbm.s558610
Primary Topic
Hemoglobinopathies and Related Disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

Haematological Profile of Patients with Sickle Cell Disease in the Acholi Sub-Region, Uganda

Christine Oryema, Jimmyy Opee, David Musoke, Geoffrey M. Malinga et al.
Journal of Blood Medicine
Hemoglobinopathies and Related Disorders
article

Haematological Profile of Patients with Sickle Cell Disease in the Acholi Sub-Region, Uganda

Christine Oryema, Jimmyy Opee, David Musoke, Geoffrey M. Malinga, Beatrice Arwenyo, Acaye Ongwech, Jackie Epila, Proscovia Nnamuyomba, Denis Ocaya, Silvia Awor, Benard Abola
article en

Abstract

In patients with sickle cell disease, there were increased white blood cells, platelets, and low red blood cells. That may reflect increased haemolytic activities that destroy the sickled red blood cells in low oxygen tension. Hydroxyurea use was associated with normal platelet counts.

Journal of Blood MedicineVol. Volume 17
Gulu University (UG), University of Liverpool (GB), Lira Hospital (UG)
Good health and well-being
Openalex Percentile: Top 55%
Hemoglobinopathies and Related Disorders
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