The association of Apolipoprotein E ε4 with symptomatic intracerebral hemorrhage, MRI markers and cognition in Dutch-type hereditary cerebral amyloid angiopathy
APOE ε4 does not affect key clinical parameters or D-CAA neuroradiological markers and therefore does not explain the large variation in disease course in D-CAA.
Authors
- Ingeborg Rasing (ORCID: https://orcid.org/0000-0002-0953-7133)
- Kevin Taddei (ORCID: https://orcid.org/0000-0002-8106-7957)
- Erik W. van Zwet (ORCID: https://orcid.org/0000-0001-5537-3179)
- Samantha L. Gardener (ORCID: https://orcid.org/0000-0002-1933-5260)
- Matthias J.P. van Osch (ORCID: https://orcid.org/0000-0001-7034-8959)
- Rosemarie van Dort (ORCID: https://orcid.org/0000-0002-7777-3189)
- Maaike C. van der Plas (ORCID: https://orcid.org/0000-0002-1437-5482)
- Steven M. Greenberg
- Gisela M. Terwindt
- Yongxi Long
- Ralph N. Martins
- Marianne A.A. van Walderveen
- Marieke J.H. Wermer
- Hamid R. Sohrabi
Institutions
- Edith Cowan University (AU)
- University Medical Center Groningen (NL)
- Harvard University (US)
- Murdoch University (AU)
- Leiden University Medical Center (NL)
- Massachusetts General Hospital (US)
- Dementia Australia (AU)
Publication Details
- Journal
- Journal of Stroke and Cerebrovascular Diseases
- Published
- 2026-02-17
- DOI
- https://doi.org/10.1016/j.jstrokecerebrovasdis.2026.108593
- Primary Topic
- Intracerebral and Subarachnoid Hemorrhage Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00