Distinct decidualization and senomorphic responses in endometrial vs. menstrual blood stem/stromal cells: implications for reproductive therapies
EnSCs and MenSCs differ in decidualization dynamics, metabolism, and response to senomorphic modulation. Senomorphics may be strategically employed to reduce senescence in patients with impaired endometrial decidualization, offering therapeutic potential in reproductive pharmacology.
Authors
- Banafsheh Tavangar
- Negar Vanaki
- Ebrahim Mirzadegan (ORCID: https://orcid.org/0000-0003-3904-9242)
- Maryam Darzi
- M R Ahmadi Mousavi
- Fazel Shokri
- Amir-Hassan Zarnani
- Soheila Arefi
Institutions
- Academic Center for Education, Culture and Research (IR)
- Biotechnology Research Center (IR)
- Tehran University of Medical Sciences (IR)
Publication Details
- Journal
- Stem Cell Research & Therapy
- Published
- 2026-02-16
- DOI
- https://doi.org/10.1186/s13287-026-04899-5
- Primary Topic
- Reproductive System and Pregnancy
- Type
- article
- Field-Weighted Citation Impact
- 0.00