Differential associations of non-chronic and chronic pain with dementia risk: insights from a cohort study
Chronic pain, especially when widespread, is associated with higher dementia risk, while non-chronic pain shows weaker or no associations. These findings suggest that both the duration and distribution of pain may play a role in dementia development and highlight the need for further research to explore underlying mechanisms.
Authors
- Runhan Fu (ORCID: https://orcid.org/0000-0002-6711-792X)
- Yongfu Lou (ORCID: https://orcid.org/0000-0002-9213-9581)
- Yanbing Kao
- Binghao Gao
- Lingxiao Chen
- Shiqing Feng
- Zhihao Zhang
Institutions
- Shandong University (CN)
- Second Hospital of Shandong University (CN)
- Qilu Hospital of Shandong University (CN)
Publication Details
- Journal
- Frontiers in Neuroscience
- Published
- 2026-02-16
- DOI
- https://doi.org/10.3389/fnins.2026.1772559
- Primary Topic
- Pain Management and Opioid Use
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Shandong University
- China Postdoctoral Science Foundation
- Natural Science Foundation of Shandong Province