The Anti-proliferative and Pro-apoptotic Effects of Iranian Viper Venom (<i>Vipera raddei kurdistanica</i>) on Human Gastric Cancer Cells (C615) are Mediated by PI3K/AKT/mTOR Signalling Pathway Inhibition.
<i>Vipera raddei kurdistanica</i> venom may exert selective cytotoxic effects against gastric cancer cells and may induce apoptosis through both intrinsic and extrinsic pathways, potentially via inhibition of the PI3K/AKT/mTOR signalling axis.
Authors
- K. Maleki
- Fuzieh Khani-Hemmatabadi (ORCID: https://orcid.org/0000-0002-3860-5713)
- Mohammadreza Gholami
- Mona Pazhouhi
- Cyrus Jalili
Institutions
- Kermanshah University of Medical Sciences (IR)
Publication Details
- Journal
- PubMed
- Published
- 2026-02-15
- DOI
- https://doi.org/10.22074/cellj.2026.2061544.1869
- Primary Topic
- Venomous Animal Envenomation and Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00