Feasibility and Safety of IL-15-Activated CD56+ Cell Therapy in High-Risk Acute Myeloid Leukemia after Hematopoietic Stem Cell Transplantation: Phase I Clinical Trial.

We identified a feasible method to activate CD56<sup>+</sup> cells and evaluate the safety of their infusion in patients. Despite the value of activating CD56<sup>+</sup> cells with IL-15, further studies with larger sample sizes are needed to confirm and validate the current hypothesi (registration number: IRCT20230801058996N2).

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Publication Details

Journal
PubMed
Published
2026-02-14
DOI
https://doi.org/10.22074/cellj.2025.2057631.1827
Citations
1
Primary Topic
Immune Cell Function and Interaction
Type
article
Field-Weighted Citation Impact
24.43
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article

Feasibility and Safety of IL-15-Activated CD56+ Cell Therapy in High-Risk Acute Myeloid Leukemia after Hematopoietic Stem Cell Transplantation: Phase I Clinical Trial.

Mozhdeh Mohammadian, Sahar Parkhideh, Amirhossein Izadpanah, Mehrshad Seresht-Ahmadi et al.
1 citations
PubMed
Immune Cell Function and Interaction
24.43
article

Feasibility and Safety of IL-15-Activated CD56+ Cell Therapy in High-Risk Acute Myeloid Leukemia after Hematopoietic Stem Cell Transplantation: Phase I Clinical Trial.

Mozhdeh Mohammadian, Sahar Parkhideh, Amirhossein Izadpanah, Mehrshad Seresht-Ahmadi, Elham Roshandel, Ahmad Gharehbaghian, Shiva Eskandarian, Mehdi Bakhtiyaridovvmbaygi, Abbas Hajifathali
article en
1 citations

Abstract

We identified a feasible method to activate CD56<sup>+</sup> cells and evaluate the safety of their infusion in patients. Despite the value of activating CD56<sup>+</sup> cells with IL-15, further studies with larger sample sizes are needed to confirm and validate the current hypothesi (registration number: IRCT20230801058996N2).

PubMedVol. 27(1)
Shahid Beheshti University (IR), Shahid Beheshti University of Medical Sciences (IR)
Good health and well-being
Openalex Percentile: Top 1%
Immune Cell Function and Interaction
24.43
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